郭娇娇

教育经历：

2014年9月-2019年6月：厦门大学 生命科学学院 生物化学与分子生物学 博士研究生

2010年9月-2014年7月：厦门大学 生命科学学院 生物技术 本科

工作简历：

2019年12月-今：内蒙古大学生命科学学院，讲师

研究兴趣：

    环境毒理学，食品毒理学

邮箱：

    gjjlife@imu.edu.cn

基金项目：

国家自然科学基金，地区项目，2023.01-2026.12，在研，主持

内蒙古自然科学基金，博士项目，2021.01-2023.12，在研，主持

内蒙古大学，高层次人才引进科研启动项目，2021.03-2022.12，在研，主持

国家自然科学基金，面上项目，斑马鱼胚胎暴露多环芳烃导致生命后期毒性效应及其表观遗传学机制，2019.01－2022.12，在研，参与

国家自然科学基金，面上项目，多氯联苯诱导糖尿病发生发展的过程及机理研究，2016.01－2019.12，已结题，参与

近年发表的文章（#表示共同第一作者；*表示通讯作者）：

15. Guo, J.#,*, Guo, W.#, Zhang, T., Zheng, Y., Han, B., Zhang, Z., Liang, N., Li, Y., Shi, Y., Zhang, X., Nashun, B*. (2022). Gestational exposure to phenanthrene induces follicular atresia and endocrine dyscrasia in F1 adult female. Ecotoxicology and Environmental Safety, 232:113291. 

14. Naren, G.#, Guo, J.#, Bai, Q., Fan, N., Nashun, B*. (2022). Reproductive and developmental toxicities of 5-fluorouracil in model organisms and humans. Expert Reviews in Molecular Medicine 24, e9, 1–6.

13. Guo, J.#, Zhang, Y.#, Li, B., Wang C*. (2021). In utero exposure to phenanthrene induced islet cell dysfunction in adult mice: Sex differences in the effects and potential causes. Science of the Total Environment, 770:145295.

12. Guo, J.#, Huang, J.#, Wang, Q., Fang, L., Zhang, S., Li, B., Lv, L., Chen, M.*, Wang C*. (2021). Maternal exposure to phenanthrene during gestation disturbs glucose homeostasis in adult mouse offspring. Chemosphere, 270, 128635.

11. Guo, J.#, Zhang, S.#, Fang, L., Huang, J., Wang, Q., Wang, C.*, Chen, M.* (2020). In utero exposure to phenanthrene induces hepatic steatosis in f1 adult female mice. Chemosphere, 258, 127360.

10. Guo J., Li B., Zuo Z., Chen M., Wang C.* (2019). Maternal supplementation with β-carotene during pregnancy disturbs lipid metabolism and glucose homoeostasis in F1 female mice. Molecular Nutrition Food Research, 2019:201900072

9. Guo, J., Wang, C., Guo, Z., Zuo, Z.* (2018). Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat. Environmental Pollution, 239:261-271.

8. Zhang, Y.#, Guo, J.#, Chen, Y., Wang, J., Zhou, Q., Chen, M.*, Wang, C.* (2021). Embryonic exposure to fenbuconazole inhibits gametogenesis in adult zebrafish by targeting gonads not brain. Ecotoxicology and Environmental Safety,  228:112967.

7. Fang, L., Guo, J., Wang, Q., Ou, K., Zou, M., Lv, L., Chen, M., Wang, C.* (2020). Chronic exposure to environmental level phenanthrene induces non-obesity-dependent insulin resistance in male mice. Environmental Science Technology DOI: 10.1021/acs.est.0c04171

6. Chen, M., Guo, J., Ruan, J., Yang, Z., He, C., Zuo, Z.* (2020) Neonatal exposure to environment-relevant levels of tributyltin leads to uterine dysplasia in rats. Science of the Total Environment, 720:137615

5. Li, B., Guo, J., Xi, Z., Xu, J., Zuo, Z., Wang, C.* (2017). Tributyltin in male mice disrupts glucose homeostasis as well as recovery after exposure: mechanism analysis. Archives of Toxicology, 91(Suppl. 1):1-9.

4. Ruan J, Guo J, Huang Y, Mao Y, Yang Z, Zuo Z.* (2019) Adolescent exposure to environmental level of PCBs (Aroclor 1254) induces non-alcoholic fatty liver disease in male mice. Environmental Research, 12:108909.

3. Xu, J., Ou, K., Chen, C., Li, B., Guo, J., et al. (2019) Tributyltin exposure disturbs hepatic glucose metabolism in male mice. Toxicology, 425:152242.

2. Dong X, Zuo Z, Guo J, et al. (2017) Reproductive effects of life-cycle exposure to difenoconazole on female marine medaka (Oryzias melastigma). Ecotoxicology, 26(6):1-10.

1.郭娇娇, 郭笑娟, 宋铁蛋, 田惠桥. (2014). 青葙花药发育的结构和组织化学观察. 亚热带植物科学, 43(2), 114-118.